- Edwards Forest Heights
- Elizabeth Heights
- Enchanted Forest
- Enoree Hills
- Edgemere
- Ellenwood Acres
- Emerald Place
- Easley
- East Gaffney
- East Sumter
- Edgefield
- Edisto
- Edisto Beach
- Ehrhardt
- Elloree
- El Bethel
- Enterprise Landing
- Elgin
- Eastover
- Elko
- Elgin
- Estill
- Elgin Acres
- Eureka Mills
- Eutawville
- Elgin Woods
- Erwin
- Evergreen Acres
- Ekom
- English Crossroads